Twiggs is closing at the end of February, though the online business will continue.
Owner Beth Patrin said sales have been slower the past couple of years, and she was ready to spend more time on the web business.
After announcing the news, Patrin arrived at the shop on a Saturday morning to find a line outside the door. The store spent six years at 48th & Chicago and six years in Linden Hills.
“There have been lots of tears and hugs,” she said. “A lot of customers don’t want to see me go, but they understand that business is business, and sometimes it is time to move on.”
“It’s time to bring some new and different energy to the corner,” Patrin said. “It’s been a really good run.”
Merchandise is on sale at discounts up to 60 percent off.
The online shop continues at shoptwiggs.com.